Address: Alyvų g. 7, Liucinavas, LT-69168 Marijampolė, Lithuania
Contact Person: Tadas Prasauskas
Telefon: +370 617 77184
We are startup of Kaunas University of Technology, with a background in chemical/environmental technology and engineering. The primary scope of our activities is converting recent advances in electrospinning and biocompatible matrixes from scientific scale to industrial scale applications. Our area of interest covers biomed and cleantech sectors, but expanding to many challenges from various industries.
The technology combines solvent-free and solvent-based electrospinning processes with additive manufacturing (3D printing). Electrospinning is a high-voltage (plasma) process, where a polymer solution or melt is subjected to a high voltage electrical field and thus is sprayed as micro and nanofibers, producing a non-woven fibrous matrixes. Produced structures have controlled fibre diameter (100 nm to 100 µm), large surface area and high porosity. A broad range of polymers can be used as raw materials. Depending on the properties of the polymer used, the applications include, but not limited to:
• biomedicine (tissue engineering);
• pharma (drug delivery);
• cleantech (filters, membranes, sensors);
• energy (electrodes, solar cells, fuel cells);
• food (packaging material, films);
• chemical engineering (carbon nanotubes, catalysts).
Why work with us:
We are not just electrospinning R&D company, although we do make our own machines from scratch. We are PhDs in chemistry and technology thus specifically underpinning the processes for your needs and applications. We spent 8 recent years researching and applying electrospinning to multiple solutions, thus having unique expertise that goes beyond simple fibre spinning.
We develop and manufacture 3D printers that print many nano and micro filaments instead of a single filament. Such modification of traditional 3D printing technique requires specific know-how of creating high-voltage electrostatic field which turns polymers to nano and microfilaments.
Fibrous design of scaffolds mimics functional structures of extracellular matrixes and provides unmatched porosity, and nano- and micrometer-scaled topologies. Functionalized nano-/microstructured materials have potential in numerous biomedical applications including wound dressing, tissue engineering, drug delivery, bioactive molecules immobilization, and separation.
Fibre-made materials are competitive in price, technology is characterized by the optimum energy consumption and is environment-friendly (no hazardous waste or emissions are produced during the process).
We provide services for the regenerative medicine sector in the development of functionalized electrospun scaffolds, closely mimicking the structure of the native environment of the cells. Fibrous matrixes are composed of fibres from nanometers to micrometers in diameter, having high porosity and large surface areas, which resemble the extracellular matrix structure in terms of the chemistry and dimensions. The process allows for control of fiber diameter, porosity, fiber orientation, hydrophilicity, surface roughness, and sample thickness.
Electrospinning techniques including solvent electrospinning, melt electrospinning, cryogenic electrospinning modification, and wet type electrospinning are employed. Bio and synthetic polymers and their blends are used for this process. Pre and post functionalization of matrixes by surface physical and chemical modification, as well as functionalization by growth factors, pharmaceuticals is provided. The matrixes can be also functionalized by the combination of nano/micro particles with nano/micro fiber structures by co-electrospraying.
Fields of application: Vascular bioengineering; Bone bioengineering; Cartilage bioengineering; Nerve bioengineering; Spinal cord bioengineering; Skin regeneration.
Matrixes for cell cultivation
We can design and produce polymeric nano/micro fiber matrices for cell cultivation and toxicity testing models. Solvent and melt electrospinning techniques are used for the production of membranes from a wide variety of polymers and their blends. Membranes with controlled fiber diameter, fiber density, pore size and porosity, hydrophilicity, size and thickness, as well as surface properties can be designed addressing the needs of specific applications.
Bioinks for bioprinting
We design and produce hydrogel based bioinks for of bioprinting in tissue engineering application. Hydrogel based bioinks can be biocompatible and biodegradable. Bioink forming stereoscopic net crosslinked structure are obtained to facilitate exchange between cells and surrounding medium. Live cells can be incorporated to bioink.
According to the needs of the customer we can design unique bioink formula from both natural and synthetic hydrogels or their blends. These bioinks may be functionalized with drugs, nutrients, growth factors to support cells survivability, proliferation, and differentiation.
Bioinks may be based on Collagen; Agarose; Chitosan; Gelatin, and Hyaluronic acid. Chemical, Photo, and physical crosslinking can be provided.
Fields of application: Skin bioengineering; Blood vessel bioengineering; Bone bioengineering, and Cosmeceuticals.